Korean J Physiol Pharmacol 2025; 29(2): 215-225

Published online March 1, 2025 https://doi.org/10.4196/kjpp.24.196

Copyright © Korean J Physiol Pharmacol.

Microglial galectin-3 increases with aging in the mouse hippocampus

Hyun Joo Shin^1,#, So Jeong Lee^1,#, Hyeong Seok An¹, Ha Nyeoung Choi², Eun Ae Jeong¹, Jaewoong Lee¹, Kyung Eun Kim¹, Bong-Hoi Choi³, Seung Pil Yun², Dawon Kang⁴, Sang Soo Kang¹, and Gu Seob Roh^1,*

¹Department of Anatomy and Convergence Medical Science, ²Department of Pharmacology and Convergence Medical Science, Institute of Medical Science, College of Medicine, Gyeongsang National University, ³Department of Nuclear Medicine and Molecular Imaging, College of Medicine, Gyeongsang National University, Gyeongsang National University Hospital, ⁴Department of Physiology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Korea

Correspondence to:Gu Seob Roh
E-mail: anaroh@gnu.ac.kr

^#These authors contributed equally to this work.

Author contributions: G.S.R. supervised and coordinated the study. H.J.S. and S.J.L. performed animal experiments and determined all protein works and histological analysis. E.A.J. quantified Sholl analysis. J.L. and K.E.K. perforemd qRT-PCR. H.S.A. and H.N.C. performed in vitro experiments. B.H.C., S.P.Y., D.K., and S.S.K. critically revised the manusctipt. S.H.J., S.J.L., and G.S.R. wrote the manuscript.