Fig. 7. Multi-electrode array (MEA) analysis of electrophysiological changes in response to drugs in hiPSC-CMs (DPHC01i-AR).
MEA analysis highlighting the percentage changes in field potential duration (FPD), corrected FPD (FPDc), beat period, and amplitude, triggered by varying concentrations of eight drugs: E4031, nifedipine, mexiletine, JNJ303, flecainide, moxifloxacin, quinidine, and ranolazine. The blue dot line indicates the 20% change threshold for FPD and FPDc. The arrow indicates the FPD20 or FPDc20, with the depth of the red color representing the decrease in FPD20 or FPDc20. hiPSC-CMs, human induced pluripotent stem cell-derived cardiomyocytes.
© Korean J Physiol Pharmacol
