Fig. 6. Multi-electrode array (MEA) study of drug-induced electrophysiological effects in hiPSC-CMs (CMC-016).
MEA study illustrating the percentage changes in electrophysiological parameters, including field potential duration (FPD), corrected FPD (FPDc), beat period, and amplitude, observed after exposure to eight drugs: E4031, nifedipine, mexiletine, JNJ303, flecainide, moxifloxacin, quinidine, and ranolazine. The blue dot line indicates the 20% change threshold for FPD and FPDc. The arrow indicates the FPD20 or FPDc20, with the depth of the red color representing the decrease in FPD20 or FPDc20. hiPSC-CMs, human induced pluripotent stem cell-derived cardiomyocytes.
© Korean J Physiol Pharmacol
