Fig. 3. RNA sequencing analysis of differential genes in mice.
(A) Scatter plot of differential gene distribution in the kidney among the control and LPS groups. (B) Histogram showing the number of up- and down-regulated differential genes in the kidney among the control and LPS groups. (C) Scatter plot of differential gene distribution in the kidney among the LPS and OPC-treated groups. (D) Histogram showing the number of up- and down-regulated differential genes in the kidney among the LPS- and OPC-treated groups. (E) Heat map showing differential gene distribution in kidney from the control, LPS, and OPC-treated groups. (F) Wenckebach plots showing the number of common differential genes before and after OPC treatment in the LPS model. (G) Bubble plots depicting KEGG signaling network enrichment of differential genes before and after OPC treatment in the LPS model. LPS, lipopolysaccharide; OPC, oligomeric proanthocyanidin; KEGG, Kyoto Encyclopedia of Genes and Genomes; Ctrl, control.
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