Fig. 3. Immunohistochemical staining of
α-SMA and collagen I in the lung tissue of mice with pulmonary fibrosis (400×). (A) Immunohistochemical staining of α-SMA. (B) Immunohistochemical staining of collagen I. The black arrow in the figure indicates positive cells. (C) and (D) present the areas of positively stained α-SMA and collagen I to represent their expression levels, respectively. The significance of difference was determined by one-way ANOVA followed by Tukey’s test. The data are presented as the means ± standard deviations. There were six mice in each group. **p < 0.01 compared with the control group. ##p < 0.01 compared with the bleomycin group.
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