Fig. 4. Comparison of predicted antioxidant activity scores for structurally similar compounds.
(A) Predicted activity scores of compounds within the chrysin network module, as determined by RF and SVM models. (B, C) Network modules for (B) eriophorin A and (C) 4-(1H-indol-2-yl)aniline. The left panel shows the network where nodes represent compounds and edges represent high structural similarity (Tanimoto coefficient exceeding 0.7). The right panel displays the corresponding predicted activity scores obtained by the RF and SVM models for each compound within the respective network module. The border color of each node indicates its experimentally determined antioxidant activity (gray for inactive, red for active). RF, Random Forest; SVM, Support Vector Machine.
© Korean J Physiol Pharmacol
