Fig. 11. Effect of DIO on the expression of AKT and VEGFA in IR + 85%PHx mice.
(A) Western blot image showing the expression levels of p-AKT, AKT, and VEGFA in the liver tissue (n = 4). (B) Increased p-AKT/AKT expression levels in the IR + 85%PHx 24 h group, **p < 0.01 (vs. Sham group); decreased p-AKT/AKT expression levels in the DIO IR + 85%PHx 24 h group, *p < 0.05 (vs. IR + 85%PHx 24 h group). (C) No difference in VEGFA expression levels in the IR + 85%PHx 24 h group compared with the Sham group. Increased VEGFA expression levels in the DIO IR + 85%PHx 24 h group, *p < 0.05 (vs. IR + 85%PHx 24 h group). Values are presented as mean ± SD. AKT, protein kinase B; VEGFA, vascular endothelial growth factor A; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IR, ischemia-reperfusion; PHx, hepatectomy; DIO, diosgenin; ns, > 0.05.
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