Fig. 5. BK channel activation increases Bk
α and Bkβ subunits, indirectly inhibiting vascular dysfunction. (A, B) Measurement of intracellular Ca2+ concentration. (B) Immunofluorescence observation of fluorescence intensity of Bkα (red) and Bkβ (green) proteins. Scale bar = 50 μm. The data were expressed as mean ± standard deviation. Data comparison between two groups was performed with the unpaired student’s t-test, and data comparison among multiple groups was conducted with a one-way analysis of variance, with Tukey’s for post-hoc test. CIH, chronic intermittent hypoxia; DMSO, dimethyl sulfoxide. *p < 0.05 compared with the control group, #p < 0.05 compared with the DMSO + CIH group.
© Korean J Physiol Pharmacol
