Fig. 4. BK channel activation curbs vascular inflammation and oxidative stress in CIH-treated rats.
(A) ROS levels. (B) MDA levels. (C) IL-6 levels. (D) TNF-α levels. (E) H&E staining results. Scale bar = 50 μm. N = 6. Data were expressed as mean ± standard deviation. Data comparison between two groups was performed with the unpaired student’s t-test, and data comparison among multiple groups was conducted with a one-way analysis of variance, with Tukey’s for post-hoc test. CIH, chronic intermittent hypoxia; ROS, reactive oxygen species; MDA, malondialdehyde; IL-6, interleukin-6; TNF-α, tumor necrosis factor alpha; DMSO, dimethyl sulfoxide. *p < 0.05 compared to the DMSO group.
© Korean J Physiol Pharmacol
