Fig. 1. Characterization of nanobody sequences.
(A) Structure of a nanobody using a ribbon diagram, highlighting the CDR1, CDR2, and CDR3 regions in pink, lime, and blue, respectively. Model structure is generated by Schrödinger software. (B) Frequency of 342 nanobody lengths as recorded in the Protein Data Bank (PDB). (C) Graphical representation of the length variability of the CDR1, CDR2, and CDR3 regions within nanobodies. (D) Sequence logo generated from a multiple sequence alignment of nanobody sequences extracted from the PDB, providing insight into conserved motifs. Sequence logo is generated by ggseqlogo of R package.
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