Table. 3.

The expression of TGFβ1, SMAD 4, SMAD 7, PAI-1 and tPA genes in HTMC after three days of incubation with resveratrol in the presence and absence of dexamethasone

Gene TGFβ1 SMAD 4 SMAD 7 PAI-1 tPA
Group 1 1.0* 1.0* 1.0* 1.0* 1.0
Group 2 1.27* 1.31* 1.18 0.93* 1.04
Group 3 2.38 2.71 0.98 3.26 1.20
Group 4 1.41* 1.38* 1.32* 1.47* 1.13
Group 5 1.49* 1.35* 2.30* 1.05* 3.47*

Data presented as fold change relative to the dexamethasone-only group (N = 3; ANOVA; *p < 0.05). Group 1, control; Group 2, vehicle; Group 3, dexamethasone only; Group 4, resveratrol only; Group 5, resveratrol and dexamethasone; HTMC, human trabecular meshwork cell.

Korean J Physiol Pharmacol 2024;28:345-359 https://doi.org/10.4196/kjpp.2024.28.4.345
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