Table. 2.

ECM gene expressions in HTMC after three days of incubation with resveratrol in the presence and absence of dexamethasone

Gene COLIA1 COLIA2 COLIIIA1 COL4A1 COL4A2 FN1 ACTA2
Group 1 1.0* 1.0* 1.0* 1.0* 1.0* 1.0* 1.0*
Group 2 1.19* 0.99* 1.18* 1.39 1.09* 0.67* 0.87*
Group 3 2.41 2.23 2.80 1.98 1.93 3.22 3.04
Group 4 1.30* 1.15* 1.30* 1.31 1.03* 0.80* 1.42*
Group 5 1.57* 1.61 2.16* 1.39 1.18* 1.92* 1.85*

Data presented as fold change relative to the dexamethasone-only group (N = 3; ANOVA; *p < 0.05). Group 1, control; Group 2, vehicle; Group 3, dexamethasone only; Group 4, resveratrol only; Group 5, resveratrol and dexamethasone; ECM, extracellular matrix; HTMC, human trabecular meshwork cell.

Korean J Physiol Pharmacol 2024;28:345-359 https://doi.org/10.4196/kjpp.2024.28.4.345
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