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Fig. 2. TR reduces ECM expressions induced by DEXA in HTMCs. Effect of TR on the (A) COLIA1 gene (B) COLIA2 gene (C) COLI protein (D) COLIIIA1 gene (E) COLIII protein (F) COLIVA1 gene (G) COLIVA2 gene (H) COLIV protein (I) FN1 gene (J) Fibronectin protein (K) ACTA2 gene and (L) Alpha smooth muscle actin protein expressions by the DEXA-treated HTMCs after treatment for three and seven days. Bars represent mean ± SD (n = 3). *p < 0.05, ANOVA with Tukey’s post-hoc. TR, resveratrol; ECM, extracellular matrix; DEXA, dexamethasone; HTMC, human trabecular meshwork cell; DMEM, Dulbecco’s modified Eagle medium; DMSO, dimethyl sulfoxide.
Korean J Physiol Pharmacol 2024;28:345-359
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