Fig. 8. 3,3′,4,4′-tetrachlorobiphenyl (PCB77) does not affect steady-state Kv1.3 current inactivation.
(A) Typical tail currents elicited by depolarizing pulses from 30 s preconditioning potentials of −80–0 to +40 mV. (B) Superimposed steady-state inactivation currents in the presence of 0 (control), 3, and 10 nM PCB77. (C) Steady-state inactivation current amplitudes were normalized to those evoked from a preconditioning potential of −60 mV. The data were fitted to the Boltzmann equation to generate the steady-state inactivation curves for each condition. Data are presented as the mean ± SEM (n = 5 oocytes per concentration).
© Korean J Physiol Pharmacol
