Fig. 4. Comparison of the effects of 3,3′,4,4′-tetrachlorobiphenyl (PCB77) on Kv1.3 and Kv1.5 currents.
(A, B) Average changes in the magnitude of steady-state (Iss) and peak current (Ipeak) evoked at +50 mV by 3 and 10 nM PCB77 treatment for 8 (A) or 15 min (B) relative to the corresponding controls. Asterisks indicate significant differences between the control in the absence of PCB77 and the indicated currents in the presence of PCB77. Daggers indicate significant differences between Kv1.3 and Kv1.5 currents in the presence of PCB77. Data are presented as the mean ± SEM (n = 4–11 oocytes per concentration treatment, *, †p < 0.05).
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