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Fig. 6. Effects of Vinp on the expression of inflammatory cytokines in skin tissue. (A–E) mRNA expression levels of IL-1β, IL-6, IL-4, TSLP, and TGF-β, respectively (n = 5 or 6). All values are presented as mean ± SD. (F) TGF-β protein levels in skin tissues were observed using Western blot (n = 4). Data were considered significant at #p < 0.1, ##p < 0.01, ###p < 0.001 compared with the control group and *p < 0.1, **p < 0.01, ***p < 0.001 compared with the DNCB group. IL, interleukin; TSLP, thymic stromal lymphopoietin; TGF, transforming growth factor; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; DNCB, 1-chloro-2,4-dinitrobenzene; Vinp, vinpocetine; Dex, dexamethasone.
Korean J Physiol Pharmacol 2024;28:303-312
© Korean J Physiol Pharmacol