Fig. 1. Increased expression levels of POLR1D and YY1 in CRC tissues and cell lines.
(A, B) The expression levels of POLR1D and YY1 in CRC patients were analyzed by GEPIA in TCGA database. (C) Kaplan–Meier method was used to analyze the correlation between POLR1D expression level and overall survival of CRC patients in TCGA database. (D, E) qRT-PCR and Western blot were applied to detect the mRNA and protein expression levels of POLR1D and YY1 in CRC cell lines. (F, G) CRC tissues and their adjacent normal tissues were collected from 22 CRC patients. qRT-PCR was used to detect the mRNA expressions of POLR1D and YY1. (H) Pearson method was used to analyze the correlation between POLR1D and YY1. Data were presented as mean ± SD. CRC, colorectal cancer. *p < 0.05, **p < 0.01, ***p < 0.001.
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