Fig. 2. Pectolinarigenin (PEC) inhibited airway obstruction and the number of inflammatory cells in cough model mice.
(A) Airway hyperresponsiveness in the OVA-induced airway inflammation model with cough group treated with the PEC and positive drug asmeton as measured by the response to different concentrations of acetylmethacholine (0, 6.25, 12.5, 25, 50 mg/ml). (B) Inflammatory cell populations (leukocytes, eosinophil, neutrophils, lymphocytes, and monocytes) in the BALF of mice was measured. Values are presented as mean ± SD. OVA, ovalbumin; BALF, bronchoalveolar lavage fluid. ^^^p < 0.001 compared with the sham group; ###p < 0.001 compared with the OVA-induced airway inflammation model with cough group.
© Korean J Physiol Pharmacol
