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Fig. 1. Pectolinarigenin (PEC) alleviated lung tissue injury in mice model with cough. (A) Pathological sections of the lung tissue were performed by H&E in the OVA-induced airway inflammation model with cough group treated with the PEC and positive drug asmeton. Mice were executed on day 30th (Scale bar: 200 μm or 100 μm). (B) Pathological sections of the lung tissue were performed by PAS in the OVA-induced airway inflammation model with cough group treated with the PEC and positive drug asmeton (Scale bar: 200 μm or 100 μm). (C) The inflammatory factor levels (TNF-α and IL-6) in BALF were assessed using ELISA. Values are presented as mean ± SD. OVA, ovalbumin; PAS, periodic acid-Schiff; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6; BALF, bronchoalveolar lavage fluid. ^^^p < 0.001 compared with the sham group; #p < 0.05, ###p < 0.001 compared with the OVA-induced airway inflammation model with cough group.
Korean J Physiol Pharmacol 2024;28:229-237 https://doi.org/10.4196/kjpp.2024.28.3.229
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