Fig. 2. The anti-proliferation activities of AM2 on a variety of bladder cancer cells.
(A) RT4, UMUC3, T24, and HUVEC cells were treated with 0, 0.25, 0.5, 1, and 2 μM of AM2 for 72 h, then observed the cell viability. (B) Comparison of the inhibitory effects of AM2 on cell proliferation in various of bladder cancer cells and HUVEC cells. (C–E) T24 cells were treated with different concentration of AM2, metformin and cisplatin for 72 h, then observed the cell viability. Data are presented as the mean ± SD of three independent experiments. ns, no significance. ****p < 0.0001.
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