Fig. 3. Mitochondrial function analysis.
(A) RCR tracked ATP production by assessing the oxygen consumption capacity of mitochondria. *p < 0.05 indicates that the group means are not all statistically equal. #p < 0.05 denoted a comparison between IR and IR + transpl. (B) mtDNA-DN assessed cellular ATP requirements. (C) Oxygen consumption per unit mitochondria was confirmed. CON (control), group without ischemia or reperfusion injury; IR, injury due to ischemia and reperfusion group; IR + transpl, group transplanted with isolated mitochondria after inducing IR injury; mtDNA-CN, mitochondrial DNA copy number; RCR, respiratory control ratio; ATP, adenosine triphosphate.
© Korean J Physiol Pharmacol
