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Fig. 4. Genus level changes in microbial distribution. (A) Gut microbial composition at genus levels before and after GEN-001 administration over time (groups A–D1). (B) Changes in the relative abundance (%) of Alistipes and Parabacteroides in the top 10 genera. (C) Changes in the relative abundance of genera used in probiotics (Lactobacillus, Lactococcus, and Bifidobacterium) after GEN-001 administration. (D) Spearman’s correlation analysis between the composition of the three probiotic genera and metabolites in fecal samples. Values are presented as mean with standard deviation. *p < 0.05.
Korean J Physiol Pharmacol 2024;28:153-164
© Korean J Physiol Pharmacol