Fig. 3. Alterations in the relative abundance of
Lactococcus lactis and Spearman’s correlation analysis between L. lactis and metabolites. Alterations in the relative abundance of L. lactis and Spearman’s correlation analysis between L. lactis and metabolites, (A) before and after GEN-001 administration, (B) with different GEN-001 doses, and (C) with or without dietary control. (D) Correlation analysis between L. lactis composition and metabolites in fecal samples 1–2 days after GEN-001 administration vs. predose. Values are presented as mean with standard deviation. Group A, four healthy adult men who take 1 × 1011 CFU; Group B, four healthy adult men who take 3 × 1011 CFU; Group C, four healthy adult men who take 6 × 1011 CFU; Group D1, four healthy adult men who take 9 × 1011 CFU without dietary control; Group D2, four healthy adult men who take 9 × 1011 CFU with dietary control; CFU, colony forming unit. *p < 0.05 and **p < 0.01.
© Korean J Physiol Pharmacol
