Fig. 1. Lithium and exercise ameliorated hyperglycemia in insulin-deficient diabetes induced by streptozotocin (STZ).
(A) Weekly body weight measurements of mice with STZ-induced hyperglycemia after lithium and/or exercise administration. (B, C) Final body weight (B) or blood glucose (C) of type 1 diabetic mice after 12 weeks of lithium and/or exercise introduction. The detailed experiment procedures are in the method section. Data are presented as means ± S.E.M. NC, saline-received normal glycemic group; PC, STZ-induced hyperglycemic group; Li, lithium(Li)-administration to STZ-received mice; Ex, moderate exercise training to STZ-received mice; Li + Ex, co-administration of Li and exercise to STZ-received mice. *p < 0.05, **p < 0.01, ***p < 0.001.
© Korean J Physiol Pharmacol
