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Fig. 4. Increasing the number of pulses per burst in the WT retina.
(A) Typical responses of the WT RGC to burst stimulation are shown as raster plots. Electrically-evoked RGC spikes are highlighted. The time window of the raster plot is set to ± 0.1 sec, with 0 sec representing the stimulus onset (red dashed line). In each raster plot (10 trials), the pulse number increases from top to bottom (#1–#5, #9–#13, #16–#20). The pulse amplitude and pulse duration are fixed with 30 μA and 100 μs/phase. Only RGCs closest 200 μm to the stimulation electrode were analyzed. (B) RGC response curves as a function of pulse number. Error bars represent the standard error of the mean (SEM). Statistical differences in the graphs are indicated by asterisks (*p < 0.05). RGC, retinal ganglion cell; WT, wild-type.
Korean J Physiol Pharmacol 2023;27:541-553
© Korean J Physiol Pharmacol