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Fig. 1. Sweroside promotes the cell viability of HK-2 cells exposed to HG.
(A) The chemical structure of sweroside. (B) The activity of cells treated with sweroside (0, 25, 50, 100 µM) under non-HG conditions were determined by CCK8 assay. (C) CCK8 assay was performed under HG exposure. (D, E) Flow cytometry analysis of cell apoptosis under HG exposure. Values are presented as mean ± SD. SW, sweroside; HK-2 cells, human renal tubular epithelial cell; HG, high glucose; Ctrl, control. NSp > 0.05, compared with non-SW group or HG group; ***p < 0.001, compared with the Ctrl group; ###p < 0.001, compared with the HG group.
Korean J Physiol Pharmacol 2023;27:533-540
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