Fig. 7. The inhibitory effects of mecheliolide, costunolide and dehydrocostus lactone on the migration of LA795 lung adenocarcinoma cells.
(A) Results of the Trans-well migration assay. Representative images recorded after mecheliolide, costunolide and dehydrocostus lactone (1, 3, 10, 30, 100 μM) treatment for 72 h. The concentration-response relationships for mecheliolide (B), costunolide (C) and dehydrocostus lactone (D) on cell migration. Data were fitted with the logistic function. (E, F) Representative images recorded after MONNA (1, 3, 10, 30, 100, 300 μM) treatment for 72 h. Bar graph show the quantification result. The results represent the means of three independent experiments. *p < 0.05, vs. the control cells in the absence of drugs.
© Korean J Physiol Pharmacol
