Fig. 6. The inhibitory effects of mecheliolide, costunolide and dehydrocostus lactone on the proliferation and migration of LA795 lung adenocarcinoma cells.
(A) Results of the CCK-8 assay. Representative images recorded after mecheliolide, costunolide and dehydrocostus lactone (1, 3, 10, 30, 100 μM) treatment for 24 h. (B–D) The concentration-response relationships for mecheliolide, costunolide and dehydrocostus lactone on cell proliferation. Data were fitted with the logistic function. (E, F) Representative images recorded after MONNA (1, 3, 10, 30, 100, 300 μM) treatment for 24 h. Bar graph show the quantification result. The results represent the means of three independent experiments. *p < 0.05, vs. the control cells in the absence of drugs.
© Korean J Physiol Pharmacol
