Fig. 2. Effect of KIF15 knockdown on the proliferation of NPC cell lines.
The mRNA (A) and protein expression (C, D) of KIF15 were detected in KIF15-shRNA/CNE-2 and ScrshRNA/CNE-2 cell lines. The mRNA (B) and protein expression (C, E) of KIF15 were detected in KIF15-shRNA/5-8F and ScrshRNA/5-8F cell lines. The cell viability (F) and relative colony formation (stained with 0.5% crystal violet staining solution) (H, I) was detected in KIF15-shRNA/CNE-2 and ScrshRNA/CNE-2 cell lines. The cell viability (G) and relative colony formation (stained with 0.5% crystal violet staining solution) (J, K) was detected in KIF15-shRNA/5-8F and ScrshRNA/5-8F cell lines. Values are presented as mean ± SD. KIF15, kinesin superfamily member 15; NPC, nasopharyngeal carcinoma. **p < 0.01 vs. the shcontrol group, n = 5.
© Korean J Physiol Pharmacol
