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Fig. 2. Effect of canagliflozin and puerarin on functional and structural parameters of kidneys. (A) Effect of canagliflozin and puerarin on urinary albumin excretion. (B) Representative image of HE (100×), PAS (400×), and picrosirius red (100×) staining of kidney sections. (C) PAS-positive area in glomeruli. (D) Percentages of picrosirius red-positive areas. Data are shown as mean ± SD (n = 6). HE, hematoxylin and eosin; PAS, periodic acid-Schiff. ##p < 0.01 vs. control group; **p < 0.01 vs. diabetes group; ^^p < 0.01 vs. canagliflozin group.
Korean J Physiol Pharmacol 2023;27:221-230
© Korean J Physiol Pharmacol