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Fig. 4. LINC00562 targeted miR-4636. (A) LncBase ( predicted LINC00562–miR-4636 binding sites. (B) Putative binding sites were validated using dual-luciferase assays, **p < 0.01 in contrast to miR-NC. (C) Binding of LINC00562 to miR-4636 was confirmed by RIP assay, **p < 0.01 in contrast to Anti-IgG. (D) MiR-4636 expression levels in tumor and normal specimens. (E) MiR-4636 expression levels in GES-1, RGM-1, and GC cells (HGC-27 and AGS), **p < 0.01 in contrast to GES-1. (F) Correlation between miR-4636 expression and LINC00562 expression in tumor samples was determined using Pearson’s analysis. Values are presented as mean ± SD. GC, gastric cancer.
Korean J Physiol Pharmacol 2023;27:197-208
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