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Fig. 6. The effect of lnc-ABCA12-3 on mitochondrial apoptosis pathway and toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) pathway in esophageal squamous cell carcinoma (ESCC) cells treated with LPS. (A) The expression of Bax, Bcl-2, caspase-3, cleaved caspase-3 were detected by Western blot. (B) The expression of TLR4, IκBα, p-IκBα, NF-κB, p-NF-κB were assessed by Western blot. Data were presented as mean ± SD. LPS, lipopolysaccharide. **p < 0.01 vs. sh-NC group, ##p < 0.01 vs. sh-ABCA12-3 group.
Korean J Physiol Pharmacol 2023;27:61-73 https://doi.org/10.4196/kjpp.2023.27.1.61
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