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Fig. 5. Lnc-ABCA12-3 regulated proliferation, glycolysis and apoptosis via activating TLR4. (A) The viability of esophageal squamous cell carcinoma (ESCC) cells were assessed by CCK-8 assay. (B, C) The proliferation was detected by EdU assay. Scale bar, 20 μm. (D–F) The contents of ATP, glucose uptake, and lactic acid production were tested by the corresponding commercial kits. (G, H) ESCC cells apoptosis were measured by flow cytometry. Data were presented as mean ± SD. TLR4, toll-like receptor 4; LPS, lipopolysaccharide. **p < 0.01 vs. sh-NC group, ##p < 0.01 vs. sh-ABCA12-3 group.
Korean J Physiol Pharmacol 2023;27:61-73
© Korean J Physiol Pharmacol