Fig. 1. Lnc-ABCA12-3 was overexpressed in esophageal squamous cell carcinoma (ESCC) tissues, serum (exosomes), and cells.
(A) Volcanic diagram of differential distribution of lncRNAs expression in microarray of ESCC and adjacent normal tissues. (B) The top 10 upregulation and downregulation of differentially expressed lncRNAs was showed in heat map. (C) Lnc-ABCA12-3 levels in normal and tumor tissues were measured by RT-PCR. **p < 0.01 vs. Normal tissues group. (D) Lnc-ABCA12-3 levels in serum from healthy people and ESCC patients were measured by RT-PCR. ##p < 0.01 vs. Control group. (E) Lnc-ABCA12-3 levels in serum-exosomes from healthy people and ESCC patients were detected by RT-PCR. &&p < 0.01 vs. Control group. (F) Lnc-ABCA12-3 levels in HEEC, TE-1, and EC9706 cells were assessed by RT-PCR. ^^p < 0.01 vs. HEEC group. Data were presented as mean ± SD.
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