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Fig. 7. Sulfur dioxide (SO2) can reverse the up-regulation of phosphatidylinositol 3-kinase (PI3K)/AKT expression induced by high glucose. (A, C) Western blot detection to observe the expression changes of P-PI3K, PI3K, P-AKT, AKT in the myocardial tissues of the rats in the Control, DC, DC + SO2, and SO2 groups. n=3; *p < 0.05 vs. Control; #p < 0.01 vs. DC. (B, D) Western blot detection was used to observe the protein expression changes of P-PI3K, PI3K, P-AKT, and AKT of H9c2 cardiomyocytes in the Control, HG, HG + SO2, HG + SO2 + 740 Y-P and SO2 group. n = 3; *p < 0.05 vs. Control. #p < 0.05 vs. HG. $p < 0.05 vs. HG + SO2. Values are presented as mean ± SD. DC, diabetic cardiomyopathy; HG, high glucose.
Korean J Physiol Pharmacol 2022;26:541-556
© Korean J Physiol Pharmacol