Fig. 7. Sulfur dioxide (SO₂) can reverse the up-regulation of phosphatidylinositol 3-kinase (PI3K)/AKT expression induced by high glucose. (A, C) Western blot detection to observe the expression changes of P-PI3K, PI3K, P-AKT, AKT in the myocardial tissues of the rats in the Control, DC, DC + SO₂, and SO₂ groups. n=3; *p < 0.05 vs. Control; ^#p < 0.01 vs. DC. (B, D) Western blot detection was used to observe the protein expression changes of P-PI3K, PI3K, P-AKT, and AKT of H9c2 cardiomyocytes in the Control, HG, HG + SO₂, HG + SO₂ + 740 Y-P and SO₂ group. n = 3; *p < 0.05 vs. Control. ^#p < 0.05 vs. HG. ^$p < 0.05 vs. HG + SO₂. Values are presented as mean ± SD. DC, diabetic cardiomyopathy; HG, high glucose.

Korean J Physiol Pharmacol 2022;26:541-556 https://doi.org/10.4196/kjpp.2022.26.6.541

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