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Fig. 4. Neogambogic acid (NGA) alleviated cardiac inflammation in septic mice. (A) NGA reduced mRNA expression of interleukin (IL)-1β, IL-18, IL-6, and TNF-α in heart tissues of lipopolysaccharide (LPS)-induced mice. (B) NGA reduced serum levels of IL-1β, IL-18, IL-6, and tumor necrosis factor-α (TNF-α) in LPS-induced mice. ** vs. sham, p < 0.01. ^^ vs. LPS, p < 0.01.
Korean J Physiol Pharmacol 2022;26:511-518
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