Table. 1.

Myocardial function of mice in each group (12 h after LPS)

Group Sham LPS LPS + 1.5 mg/kg LPS + 3 mg/kg LPS + 6 mg/kg
EF (%) 72.04 ± 1.88 49.62 ± 4.28* 55.34 ± 2.15# 61.16 ± 5.43# 65.85 ± 1.48#
FS (%) 44.25 ± 3.13 20.65 ± 2.26* 27.16 ± 2.04# 32.78 ± 4.90# 40.09 ± 5.21#
LVSP (mmHg) 108.94 ± 1.65 50.25 ± 3.63* 68.33 ± 3.54# 79.43 ± 2.12# 88.21 ± 4.21#
LVEDP (mmHg) 4.09 ± 2.32 10.47 ± 1.23* 8.75 ± 0.23 6.41 ± 1.19# 5.02 ± 2.09#

Values are expressed as mean ± SE (n = 6 per group). LPS, lipopolysaccharide; EF, ejection fraction; FS, fractional shortening; LVSP, left ventricular systolic mean pressure; LVEDP, left ventricular end-diastolic pressure. *p < 0.05 vs. Sham; #p < 0.05 vs. LPS.

Korean J Physiol Pharmacol 2022;26:511-518 https://doi.org/10.4196/kjpp.2022.26.6.511
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