Fig. 1. Neogambogic acid (NGA) alleviated cardiac injury and dysfunction in septic mice.
(A) Lipopolysaccharide (LPS) induced disordered myofilament arrangement and edema of myocardial tissues, injection with neogambogic acid attenuated histopathological changes in myocardial tissues of LPS-induced mice using H&E staining. Magnification: x200. (B) NGA reduced serum level of lactate dehydrogenase (LDH) in septic mice. (C) NGA reduced serum level of creatine kinase-MB (CK-MB) in septic mice. (D) NGA reduced serum level of creatine troponin I (cTnI) in septic mice. ** vs. sham, p < 0.01. ^, ^^ vs. LPS, p < 0.05, p < 0.01.
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