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Fig. 7. Arctigenin reduced the phosphorylation of proteins in the MAPKs, NF-κB, and AKT pathways in FaDu pharyngeal cells. FaDu cells were treated with 0, 50, and 100 μM Arctigenin for 24 h. Thereafter, immunoblotting using specific antibodies against extracellular signal-regulated kinase 1/2 (ERK1/2), p38, NFκB, and AKT was performed to verify potential cellular signaling pathways associated with Arctigenin-induced apoptosis.
Korean J Physiol Pharmacol 2022;26:447-456
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