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Fig. 3. Induction of cell death by Arctigenin. (A) L-929 cells and FaDu cell death by Arctigenin. The cells were treated with 0, 50, or 100 μM Arctigenin for 24 h. Arctigenin induced the death of FaDu cells in the dose-dependent manner. FaDu cells emitting green fluorescence are live cells stained by green calcein AM, whereas cells emitting red fluorescence are dead cells stained by ethidium homodimer-1. The arrows indicate dead cells stained red. Scale bar represents 100 µm. (B) Quantitative data of (A) were counted, and calculated as 100%. Each data point represents the mean ± SEM of four experiments. **p < 0.01 vs. control and ***p < 0.001 vs. control (the control cells measured in the absence of Arctigenin).
Korean J Physiol Pharmacol 2022;26:447-456
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