Fig. 7. Effects of myricetin (MYR) on the expression of brain-derived neurotrophic factor (BDNF) and tropomyosin-related kinase B (TrkB) mRNA in rats with sleep deprivation (SD)-induced hippocampal impairment.
(A) PCR bands on agarose gels and relative intensities are shown. Expression levels of BDNF and TrkB mRNAs were normalized to glyceraldehyde 3-phosphate dehydrogenase mRNA as the internal control, (B) activation of nuclear factor kappa B (NF-κB) in the hippocampus after MYR treatment. Western blot analysis of protein expression levels of NF-κB. SAL, saline; WPF, wide platform; ATI, alprazolam. *p < 0.05, ***p < 0.001 vs. SAL group; #p < 0.05, ##p < 0.01 vs. SD group.
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