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Fig. 3. Effects of oxytocin on pAkt (Tyr 473) and peNOS (Ser 1177) expressions in the rat aorta ex vivo. Incubation of oxytocin (10 nM) for 5 min ex vivo significantly increased pAkt (Tyr 473, A) and peNOS (Ser 1177, B) expression. Either wortmannin or atosiban prevented oxytocin-indued pAkt (C) and peNOS (D) expression. OT, oxytocin; Wort, wortmannin; Ato, atosiban. n = 8, *p < 0.05 vs. control group; #p < 0.05 vs. oxytocin group.
Korean J Physiol Pharmacol 2022;26:255-262
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