Download original image
Fig. 7. PI3K inhibitor LY294002 inhibits the migration of 16HBE cells. (A, B) The PI3K inhibitor LY294002 was used to study effects on the migration of 16HBE cells transfected with NC, miR-21 mimics, or PARP-1 siRNA. The experiments were replicated three times and presented as mean ± SD. 16HBE, Human bronchial epithelial cell; NC, normal control; miR-21, microRNA-21; PARP-1, poly (ADP-ribose) polymerase-1; siRNA, small interfering RNA; siPARP-1, PARP-1 siRNA; D, dimethylsulfoxide; LY, LY294002. Scale bars = 50 μm. *p < 0.05 vs. NC + D group, ***p < 0.001 vs. NC + D group, ††p < 0.01 vs. siPARP-1 + D group, †††p < 0.001 vs. miR21 + D group.
Korean J Physiol Pharmacol 2022;26:239-253
© Korean J Physiol Pharmacol