Download original image
Fig. 1. PARP-1 inhibits the migration of 16HBE cells. (A, B) Western blot and qRT-PCR were performed to evaluate the protein and mRNA expressions of PARP-1 in 16HBE cells transfected with NC, PARP-1 plasmid, or PARP-1 siRNA after 48 h. The experiments were replicated three times and presented as mean ± SD. *p < 0.05 vs. NC group. (C) Effects of PARP-1 on migration in 16HBE cells were detected by Transwell assay. Scale bars = 50 μm. The experiments were replicated three times and presented as mean ± SD. PARP-1, poly (ADP-ribose) polymerase-1; 16HBE, Human bronchial epithelial cell; NC, normal control; siRNA, small interfering RNA; siPARP-1, PARP-1 siRNA. *p < 0.05 vs. NC group, **p < 0.01 vs. NC group.
Korean J Physiol Pharmacol 2022;26:239-253 https://doi.org/10.4196/kjpp.2022.26.4.239
© Korean J Physiol Pharmacol