Fig. 3. Effects of TRPM2-specific shRNA on glycine (1 mM)-induced increase in [Ca2+]i in neutrophils (A), and on glycine (500μM)-induced enhancement of bactericidal activity (B).
Neutrophils were transfected with shRNA against TRPM2. After 24 h, the effects of glycine on [Ca2+]i. in neutrophils (A) and bactericidal activity (B) were assayed. The average of three experiments is shown (mean ± SE). *p < 0.05 by Student’s t-test.
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