Download original image
Fig. 6. Oxymatrine affected DNA-binding activity of NF-κB (p65) and Nrf2 in INS-1 cells. (A) Analysis of the DNA-binding activity of NF-κB (p65). (B) Analysis of the DNA-binding activity of Nrf2. Control: no treatment; HG: high glucose (30 mM glucose); PA: palmitic acid sodium (400 μM); Oxymatrine: 10 μM . Data are presented as mean ± SD and represent an average of three experiments. NF-κB, nuclear factor kappa B; Nrf2, nuclear factor (erythroid-derived 2)-like 2 protein. Data are normalized to control. **p < 0.01 vs. control, #p < 0.05, ## p < 0.01 vs. HG + PA; the experiments were repeated three times.
Korean J Physiol Pharmacol 2022;26:165-174
© Korean J Physiol Pharmacol