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Fig. 3. Oxymatrine inhibited high glucose and high fat-induced ROS production in INS-1 cells. (A) Representative graphics of ROS production were showed. (B) The ROS production from different cells. control: no treatment; HG: high glucose (30 mM glucose); PA: palmitic acid sodium (400 μM); Oxymatrine: 10 μM. Data are presented as mean ± SD and represent an average of three experiments. ROS, reactive oxygen species; DCFH-DA, Dichloro-dihydro-fluorescein diacetate; MFI, mean fluorescence intensity. Data are normalized to control. **p < 0.01 vs. control, #p < 0.05 vs. HG + PA; the experiments were repeated three times.
Korean J Physiol Pharmacol 2022;26:165-174
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