Fig. 5. DSF does not significantly induce myelosuppression in vivo.
The mice were intraperitoneally injected with 50 mg/kg DSF every 2 days, on day 0, 2, and 4 (A). Control mice were injected with DMSO alone. The mice were sacrificed at indicated times and BMs were harvested. The cellularity of BMs was calculated using the trypan blue exclusion test. The graph was generated using in vivo data of 12 mice in each group from more than three independent experiments (B). The representative subset proportion (C) and the percentage of positive cells (D) were presented. DSF, disulfiram; DMSO, dimethyl sulfoxide; BMs, bone marrow cells; ns, non-significant.
© Korean J Physiol Pharmacol