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Fig. 2. The resistance index of resistant cell line of K562/DOX and A2780/Taxol. (A) Cell survival rate of different concentration of DOX on K562 and K562/DOX. (B) IC50 (µmol/L) values were calculated from survival curves using the Bliss method and then RI was calculated by dividing the IC50 for K562/DOX cells by that of K562 cells. (C) Cell survival rate of different concentration of Taxol on A2780 and A2780/Taxol. (D) IC50 (µM) values were calculated from survival curves using the Bliss method and then RI was calculated by dividing the IC50 for A2780/DOX cells by that of A2780 cells. Taxol, Taxinol; DOX, doxorubicin; IC50, 50% inhibiting concentration; RI, resistance index.
Korean J Physiol Pharmacol 2022;26:145-155 https://doi.org/10.4196/kjpp.2022.26.3.145
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