Fig. 3. Peiminine ameliorated myocardial infarction-induced inflammation and apoptosis in rats.
(A) Peiminine administration suppressed the myocardial infarction-induced increase of CK-MB in rats detected by ELISA. (B) Peiminine administration inhibited myocardial infarction-induced increase of myocardial cell apoptosis in rats detected by TUNEL staining (×200). (C) Peiminine administration inhibited the myocardial infarction-induced increase of Bax and decrease of Bcl-2 in rats detected by Western blot. CK-MB, creatine kinase-MB; IL, interleukin; TNF, tumor necrosis factor. ** vs. sham, p < 0.01. ## vs. myocardial infarction (MI), p < 0.01.
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